Advanced Treatment for Brain Tumors

The Penn Brain Tumor Center treats all types of brain tumors, regardless of the tumor's stage. Few health systems have access to the scope of brain tumor treatments available at Penn Medicine. The Penn Brain Tumor Center provides innovative surgical and non-surgical options for complex and inoperable brain tumors of all types, including:

  • Acoustic neuroma
  • Astrocytoma
  • Blastoma
  • Brain Tumor (primary or metastatic)
  • Cranial- or skull-based
  • Glioblastoma (GBM)
  • Glioma
  • Meningioma
  • Oligodendroglioma
  • Pituitary
  • Schwannoma

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The Most Advanced Treatment Options

Penn Medicine offers the region's most comprehensive treatments - including proton therapy - for benign (non-cancerous) and malignant tumors originating in the brain, as well as metastatic brain cancer:

Download Brain Tumor Treatment Guide

Download Guide

Proton Therapy

Proton therapy is a form of external beam radiotherapy in which protons (hydrogen atoms from which the electrons have been removed) are directed at a tumor site.



CyberKnife is a noninvasive alternative to surgery for treating cancerous and noncancerous tumors anywhere in the body.

gamma knife

Gamma Knife Perfexion™

Gamma Knife Perfexion therapy is one of the most precise, powerful and proven treatments for brain disorders. Download FAQ Sheet (PDF)



Intensity-modulated radiation therapy (IMRT) is an advanced type of radiotherapy uses a computer-controlled device to deliver precise doses of radiation to specific areas within the tumors.



In most cases, the first step in brain tumor treatment is to surgically remove as much of the tumor as possible without affecting normal brain tissue or function.

Download Brain Tumor Treatment Guide

Brain Tumor Treatment Guide

brain tumor guide 2

If you or a loved one been diagnosed with a brain tumor, you likely have many questions about the diagnosis, treatment and the recovery process. This guide will help you understand your condition and describe what you need to know in order to make the right medical decision.

Download Free Brain Tumor Guide

Experienced Brain Tumor Team

When considering where to be treated for a brain tumor, the experience of the team is of utmost importance. Penn's neurosurgeons are among the most skilled and recognized in the world. They work in a multidisciplinary team setting and collaborate with other experienced specialists to offer complete care.


Speak with a Nurse Navigator

Receiving a brain tumor diagnosis can be an overwhelming time for patients and caregivers.

Our brain tumor nurse navigator is a part of the overall care team and helps patients determine which specialist to see, coordinates appointments, provides easier access to the many resources available at Penn, and offers general support to patients and families.

Speak with a brain tumor nurse navigator today to:

  • Schedule an appointment
  • Get a second opinion
  • Ask a question
  • Find a clinical trial
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